Home » Active Pharmaceuticals Ingredients » Disulfiram
Product Name | Disulfiram BP/EP/USP |
Chemical Name | 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane |
CAS Number | 97-77-8 |
Chemical Formula | C10H10N2S4 |
Molecular Mass | 296.54 g/mol |
Therapeutic Category | - |
Specification of Disulfiram :
Test | Specification |
Description | A white to almost white crystalline powder |
Solubility | Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in alcohol |
Identification A) Melting range B) By IR C) By TLC D) By chemical |
Between 70º c and 73º c The IR. Spectrum is concordant with spectrum obtained from Disulfiram working standard. The principal spot obtained in the chromatogram with Disulfiram test solution should be similar in position and size to the principal spot obtained in the chromatogram with Disulfiram working standard A yellow color develops which becomes greenish-yellow |
Diethyldithiocarbamate | NMT 150 ppm |
Loss on drying | NMT 0.5% w/w |
Sulphated ash | NMT 0.1% |
Heavy metals | NMT 20 ppm |
Related substances By TL | NMT 0.5% |
Assay (ODB) | Between 98.5% & 101 % |
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